Researchers at the Libin Cardiovascular Institute are supported by several core service facilities that provide expertise on everything from data analysis to pathology.
Mozell Family Analysis Core Lab is a shared resource centre within the Libin Cardiovascular Institute that manages health data, provides biostatistical and analytical consultation and translates information into knowledge for action. Its mandate is to improve and enhance the quality of research conducted within the institute and increase investigators's productivity. Its services are available to faculty, staff, and students of the Libin Institute.
- Enhancement for research activities within the Libin Cardiovascular Institute
- Statistical consultation and expertise for members of the Libin Cardiovascular Institute
- Study design and sample size calculation for grant proposals
- Health data management, statistical analysis and interpretation of results for research reports, manuscripts and conference presentations.
- Zhiying (Jane) Liang, MSc (Statistical Associate)
- Dr. Hude Quan (Principal Investigator)
Located in Health Research Innovation Centre (HRIC) GB44, the Core Pathology Lab is a shared resource centre within the Libin Cardiovascular Institute to manage and process human and animal tissue, cultured cells and artificial samples. Services are open to all University of Calgary principal investigators, including their staff and students.
Currently, users may leave samples with Core Pathology Lab staff members, who will process each sample. When complete, users may pick up their result(s) and/or slide(s), or the Core Pathology Lab may photograph the result(s) and e-mail it to the user. Turnaround time will depend on volume.
Contact Dr. Yong-Xiang Chen, Core Pathology Technician at firstname.lastname@example.org, for more information.
The Centre for Health Informatics is the newest University of Calgary research and innovation centre within the Cumming School of Medicine. The Centre came into existence in 2018 to advance the mandate of the Cumming School of Medicine’s focus on precision medicine and precision public health.
The purpose of the cardiovascular physiology core is to aid members of the Libin Cardiovascular Institute in their research to understand the impact of disease on the heart and vascular system. This support is mediated through the development and characterization of cardiovascular disease models (small animal: mouse and rat) and the ability to visualize and characterize the phenotypic changes associated with these models.
Our non-invasive cardiovascular phenotyping is accomplished through echo analysis of heart and vascular function using a Vevo-3100 echocardiography machine. This echo machine is capable of providing B-Mode and M-Mode measurements of the heart and vasculature with high resolution capable of measuring blood vessels as small as a mouse coronary artery. Colour flow Doppler, Tissue Doppler and Pulse Wave Doppler are used to examine mitral valve activity in heart and the response of blood vessels to various treatments.
The core has established models of heart disease such as coronary artery ligation for myocardial infarction (MI), transverse aortic constriction (TAC) for cardiac hypertrophy, vascular surgery for aneurysm development, as well as experience with the application of vectors (adenovirus/plasmid/exosome) involved in altering the phenotype of the heart. Cardiac function and blood pressure measurements are obtained through pressure catheters and pressure-volume (PV) loop analysis.
Additional assistance in tissue collection and preparation for gene/protein expression and analysis, as well as the development of specialized systems for the analysis of cardiac function (Langendorf, isolated working heart system) are available.
- Small animal surgery
- Lab work
The rate for use of the Cardiovascular Physiology Core is $35/hr.
For more information contact Dr. Darrell Belke, PhD, at email@example.com.
The Cumming School of Medicine’s Clinical Trials Core is made up of several groups that offer everything from coordination of research to data, methods and quality assurance.
The Calgary Centre for Clinical Research
The Calgary Centre for Clinical Research (CCCR) coordinates research projects. It's services are open to faculty. Contact firstname.lastname@example.org.
Heritage Medical Research Clinic
The Heritage Medical Research Clinic (HMRC) is located at the Foothills Hospital Campus on the fifth floor of the Teaching Research and Wellness Building. Set up to accommodate the needs of researchers, the agency merges patient care with clinical trials. Contact Sabine Moritz at email@example.com for more information.
Clinical Research Unit
The Clinical Research Unit works with researchers in the Cumming School of Medicine to support the delivery of cutting-edge research support services in the area of data, technology and methodology. Contact Lori Campbell at firstname.lastname@example.org for more information.
Quality Assurance Program
The Quality Assurance and Regulatory Compliance Specialist assesses research quality, verifying research studies are conducted and data is generated, documented and recorded in compliance with the study protocol, applicable regulations, standards operating procedures and institutional policies. For more information, contact Jenna Dobry at email@example.com.
Centre for Mobility and Joint Health
The Centre for Mobility and Joint Health (MoJo) is located within the McCaig Institute in the Cumming School of Medicine. Researchers within the centre use state-of-the-art imaging, motion assessment and diagnostic equipment to assess individual bone and joint health on every level. MoJo's researchers work with the Alberta Health System, physicians and patients to develop new technologies for the prevention, early diagnosis and treatment of bone and joint conditions. Contact Yves Pauchard at firstname.lastname@example.org for more information.