David Montero Barril

Research Collaborator

Exercise/Cardiovascular Physiology


University of Avignon, France

Contact information


Office : KNB 2212


Research areas

  • Blood volume
  • blood volume-cardiac interactions
  • plasma volume
  • hemoglobin mass
  • aerobic capacity
  • heart failure/diabetes/renal pathophysiology


Control over daily actions that improve our quality of life has aroused a constant fascination in me for as long as I can remember. For the last two decades I have been exposed to diverse education/research paradigms in different countries (Spain, Italy, France, Netherlands, Switzerland, Denmark, Canada). During this time, I have developed my own vision of what constitutes the essential questions in human physiology, specifically regarding the cardiovascular system in health and disease, an integrative topic par excellence. My research interests converge upon fundamental mechanisms of cardiac function, with particular emphasis on the interaction of cardiovascular and hematological systems. Embracing integrative approaches, my work aims to elucidate the pathophysiological basis of impaired cardiac function and blood volume dysregulation (e.g., anemia, hypovolemia) associated with cardiovascular disease in humans.



Montero D, Diaz-Canestro C, Oberholzer L, Lundby C. The role of blood volume in cardiac dysfunction and reduced exercise tolerance in patients with diabetes mellitus. Lancet Diabetes Endocrinol 2019.

Montero D, Lundby, C. Regulation of red blood cell volume with exercise training. Compr Physiol 2018.

Montero D, Lundby, C. Arterial O2 content regulates plasma erythropoietin independently of arterial O2 tension: a blinded crossover study. Kidney Int 2018.

Montero D, Breenfeldt-Andersen A, Oberholzer L, Haider T, Goetze JP, Meinild-Lundby AK, Lundby C. Erythropoiesis with endurance training: dynamics and mechanisms. Am J Physiol Regul Integr Comp 2017.

Montero D, Madsen K, Meinild-Lundby AK, Edin F, Lundby C. Sex dimorphism of substrate utilization: differences in skeletal muscle mitochondrial volume density and function. Exp Physiol 2018.

Montero D, Lundby C. Red cell volume response to exercise training: association with aging. Scand J Med Sci Sports 2016 October 18.

Montero D, Lundby C. Refuting the myth of non-response to exercise training: ‘non-responders’ do respond to higher dose of training. J Physiol 2016.

Montero D, Diaz-Cañestro C, Keiser S, Lundby C. Arterial stiffness is strongly and negatively associated with the total volume of red blood cells. Int J Cardiol 2016.

Montero D, Houben AJ, Koster A, Muris DM, Schram MT, Gronenschild EH, Sep SJ, Henry RM, van der Kallen CJ, Schaper NC, Dagnelie PC, van Geel TA, Kremers SP, Savelberg HH, Stehouwer CD. Physical activity is associated with glucose tolerance independent of microvascular function: the Maastricht Study. JCEM 2016.

Montero D, Rauber S, Goetze JP, Lundby C. Reduction in central venous pressure enhances erythropoietin synthesis: role of volume-regulating hormones. Acta Physiol (Oxf) 2016.

Montero D, Cathomen A, Jacobs RA, Flück D, Leur J, Keiser S, Bonne T, Kirk N, Lundby AK, Lundby C. Haematological rather than skeletal muscle adaptations contribute to the increase in peak oxygen uptake induced by moderate endurance training. J Physiol 2015.

Montero D, Diaz-Cañestro, C. Endurance training and VO2max with ageing: role of maximal cardiac output and oxygen extraction. Eur J Prev Cardiol 2015.

Montero D, Padilla J, Diaz-Cañestro C, Muris DM, Pyke KE, Obert P, Walther G. Flow-mediated dilation in athletes: influence of aging. Med Sci Sports Exerc 2014.

Montero D, Walther G, Perez-Martin A, Mercier CS, Roche E, Vinet A. Leg arterial stiffness after weight loss in severely obese adolescents. Int J Cardiol 2013.