Stack of papers

Manuscripts

APPROACH began publishing peer-reviewed papers in April 2000, after having collected 5 years of data. The following is a list of citations for manuscripts published since then. Clicking on each title will lead to the manuscript's abstract. 

Ozemek C, Arena R; Rouleau CR, Campbell TS, Hauer T, Wilton SB, Stone J, Laddu D, Williamson TM, Liu H, Chirico D, Austford LD, Aggarwal S. Long-Term Maintenance of Cardiorespiratory Fitness Gains After Cardiac Rehabilitation Reduces Mortality Risk in Patients With Multimorbidity. Journal of Cardiopulmonary Rehabilitation and Prevention. (2022).

Liu H, Southern DA, Arena R, Sajobi T, Aggarwal S, James MT, Wilton SB. Cardiac Rehabilitation and Risk of Incident Atrial Fibrillation in Patients With Coronary Artery Disease. Canadian Journal of Cardiology 38(10) 1621-1628 (2022).

Lawal, O.A., Awosoga, O., Santana, M.J. et al. Measurement invariance of the Seattle Angina Questionnaire in coronary artery disease. Qual Life Res 31, 1223–1236 (2022).

Ma B, Faris P, Har BJ, Tyrrell B, Benterud E, Spertus JA, Pannu N, Manns BJ, Graham MM, James MT. Development and Evaluation of an Audit and Feedback Process for Prevention of Acute Kidney Injury During Coronary Angiography and Intervention. CJC Open 4(3), 271-281 (2022).

James MT, Har BJ, Tyrrell BD, et al. Effect of Clinical Decision Support With Audit and Feedback on Prevention of Acute Kidney Injury in Patients Undergoing Coronary Angiography: A Randomized Clinical Trial. JAMA. 2022;328(9):839–849.

Hijazi W, Leslie W, Filipchuk N, Choo R, Wilton S, James M, Slomka PJ, Miller RJH. External validation of the CRAX2MACE model. J Nucl Cardiol. 2022.

de Souza ESCG, Buginga GC, de Souza e Silva ESEA, Arena R, Rouleau CR, Aggarwal S, Wilton SB, Austford L, Hauer T, Myers J. Prediction of Mortality in Coronary Artery Disease: Role of Machine Learning and Maximal Exercise Capacity. Mayo Clinic Proceedings. 2022.

Bianco, M., Careggio, A., Biolè, C.A. et al. Ticagrelor or Clopidogrel After an Acute Coronary Syndrome in the Elderly: A Propensity Score Matching Analysis from 16,653 Patients Treated with PCI Included in Two Large Multinational Registries. Cardiovasc Drugs Ther35, 1171–1182 (2021)

Zhang D, Song X, Raposeiras-Roubín S, Abu-Assi E, Simao Henriques JP, D'Ascenzo F, Saucedo J, González-Juanatey JR, Wilton SB, Kikkert WJ, Nuñez-Gil I, Ariza-Sole A, Alexopoulos D, Liebetrau C, Kawaji T, Moretti C, Huczek Z, Nie S, Fujii T, Correia L, Kawashiri MA, Southern D, Kalpak O. Evaluation of optimal medical therapy in acute myocardial infarction patients with prior stroke. Ther Adv Chronic Dis. 2021 Sep 29;12:20406223211046999

Wilson T, Javaheri P, Finlay J, Hazlewood G, Wilton SB, Sajobi T, Levin A, Pearson W, Connolly C, James MT. Treatment Preferences for Cardiac Procedures of Patients With Chronic Kidney Disease in Acute Coronary Syndrome: Design and Pilot Testing of a Discrete Choice Experiment. Can J Kidney Health Dis. 2021 Jan 27;8:2054358120985375.

Liu H, Collins R, Miller RJH, Southern DA, Arena R, Aggarwal S, Sajobi T, James MT, Wilton SB. Use of a Clinical Electrocardiographic Database to Enhance Atrial Fibrillation/Atrial Flutter Identification Algorithms Based on Administrative Data. Am Heart Assoc. 2021 Apr 6;10(7):e018511.

Malebranche D, Hasan S, Fung M, Har B, Champagne P, Schnell G, Wilton SB, Anderson TJ. Patterns of Left-Ventricular Function Assessment in Patients With Acute Coronary Syndromes. CJC Open. 2021 Feb 1;3(6):733-740.

Trpkov C, Savtchenko A, Liang Z, Feng P, Southern DA, Wilton SB, James MT, Feil E, Mylonas I, Miller RJH. Visually estimated coronary artery calcium score improves SPECT-MPI risk stratification. Int J Cardiol Heart Vasc. 2021 Jun 19;35:100827.

Thompson S, Wiebe N, Arena R, Rouleau C, Aggarwal S, Wilton SB, Graham MM, Hemmelgarn B, James MT. Effectiveness and Utilization of Cardiac Rehabilitation Among People With CKD. Kidney Int Rep. 2021; 6, 1537–1547.

Lawal OA, Awosoga O, Santana MJ, James MT, Wilton SB, Norris CM, Lix LM, Sajobi TT. Measurement invariance of the Seattle Angina Questionnaire in coronary artery disease Quality of Life Research. 2021 Sep 8.

Boothby CA, Santana MJ, Norris CM, Campbell TS, Rabi DM. Sexual Activity After Acute Coronary Syndrome A Qualitative Approach to Patient and Partner Experiences J Cardiovasc Nurs. 2021 Sep-Oct 01;36(5):E71-E79.

Thompson S, Wiebe N, Arena R, Rouleau C, Aggarwal S, Wilton SB, Graham MM, Hemmelgarn B, James MT. Effectiveness and Utilization of Cardiac Rehabilitation Among People With CKD. Kidney International Reports, 2021; 6(6): 1537-47.

Lee S, Li, Bing B, Martin EA, D'Souza AG, Jiang J, Doktorchik C, Southern DA, Lee J, Wiebe N, Quan H, Eastwood CA. CREATE: A New Data Resource to Support Cardiac Precision Health. CJC Open. 2020 Dec 27;3(5):639-645.

Fatehi Hassanabad, A., Aboelnazar, N., Maitland, A., Holloway, D. D., Adams, C., & Kent, W. D. Right anterior mini thoracotomy approach for isolated aortic valve replacement: Early outcomes at a Canadian center. Journal of Cardiac Surgery.

D'Ascenzo, F., De Filippo, O., Gallone, G., Mittone, G., Deriu, M. A., Iannaccone, M., ... & Arfat, Y. (2021). Machine learning-based prediction of adverse events following an acute coronary syndrome (PRAISE): a modelling study of pooled datasets. The Lancet, 397(10270), 199-207.

Finlay, J., Wilson, T., Javaheri, P. A., Pearson, W., Connolly, C., Elliott, M. J., ... & James, M. T. (2020). Patient and physician perspectives on shared decision-making for coronary procedures in people with chronic kidney disease: a patient-oriented qualitative study. TCMAJ open, 8(4), E860-E868.

Gerling, M. E., Dong, Y., Abdalla, B., James, M. T., Wilton, S. B., Naugler, C. T., ... & APPROACH Investigators. (2020). Simple Laboratory Test-Based Risk Scores in Coronary Catheterization: Development, Validation, and Comparison to Conventional Risk Factors. The Journal of Applied Laboratory Medicine, 5(4), 616-630.

Lawal, O. A., Awosoga, O., Santana, M. J., James, M. T., Southern, D. A., Wilton, S. B., ... & Ghali, W. A. (2020). Psychometric evaluation of a Canadian version of the Seattle Angina Questionnaire (SAQ-CAN). Health and Quality of Life Outcomes, 18(1), 1-10. 377 (2020).

Bainey, K. R., Alemayehu, W., Armstrong, P. W., Westerhout, C. M., Kaul, P., & Welsh, R. C. (2020). Long-term outcomes of complete revascularization with percutaneous coronary intervention in acute coronary syndromes. JACC: Cardiovascular Interventions, 13(13), 1557-1567.

Liu, X., Bertazzon, S., Villeneuve, P. J., Johnson, M., Stieb, D., Coward, S., ... & Rabi, D. (2020). Temporal and spatial effect of air pollution on hospital admissions for myocardial infarction: a case-crossover study. CMAJ open, 8(4), E619.

Turgeon, R. D., Koshman, S. L., Youngson, E., Har, B., Wilton, S. B., James, M. T., & Graham, M. M. (2020). Association of ticagrelor vs clopidogrel with major adverse coronary events in patients with acute coronary syndrome undergoing percutaneous coronary intervention. JAMA Internal Medicine, 180(3), 420-428.

Ezekowitz, J. A., Savu, A., Welsh, R. C., McAlister, F. A., Goodman, S. G., & Kaul, P. (2020). Is There a Sex Gap in Surviving an Acute Coronary Syndrome or Subsequent Development of Heart Failure? Circulation, 142(23), 2231-2239.

Tran DT, Barake W, Galbraith D, Norris C, Knudtson ML, Kaul P, McAlister FA, Sandhu RK. Total and Cause-Specific Mortality After Percutaneous Coronary Intervention: Observations From the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease Registry. CJC Open 2019 Jul; 1(4): 182-9.

Hong, Y., Graham, M. M., Rosychuk, R. J., Southern, D., & McMurtry, M. S. (2019). The Effects of Acute Atmospheric Pressure Changes on the Occurrence of ST-Elevation Myocardial Infarction: A Case-Crossover Study. Canadian Journal of Cardiology, 35(6), 753-760.

Liu, H., Wilton, S. B., Southern, D. A., Knudtson, M. L., Maitland, A., Hauer, T., ... & Aggarwal, S. (2019). Automated Referral to Cardiac Rehabilitation After Coronary Artery Bypass Grafting Is Associated With Modest Improvement in Program Completion. Canadian Journal of Cardiology, 35(11), 1491-1498.

Ma, B., Allen, D. W., Graham, M. M., Har, B. J., Tyrrell, B., Tan, Z., ... & Pannu, N. (2019). Comparative Performance of Prediction Models for Contrast-Associated Acute Kidney Injury After Percutaneous Coronary Intervention. Circulation: Cardiovascular Quality and Outcomes, 12(11), e005854.

McRae, A., Graham, M., Abedin, T., Ji, Y., Yang, H., Wang, D., ... & Seiden-Long, I. (2019). Sex-specific, high-sensitivity cardiac troponin T cut-off concentrations for ruling out acute myocardial infarction with a single measurement. Canadian Journal of Emergency Medicine, 21(1), 26-33.

Hong Y, Graham M, Southern D, McMurtry M. The association between chronic obstructive pulmonary disease and coronary artery disease in patients undergoing coronary angiography. COPD: Journal Of Chronic Obstructive Pulmonary Disease COPD 2019 Feb; 16(1):66-71.

Armstrong MJ, Rabi DM, Southern DA, Nanji A, Ghali WA, Sigal RJ. Clinical Utility of Pre-exercise Stress Testing in People with Diabetes. Canadian Journal of Cardiology 2019; 35 (2), 185-192

Wang M, Norris C, Graham M, Santana M, Liang Z, Awosoga O, Southern D, James M, Wilton S, Quan H, Lu M, Ghali W, Knudtson M, Sajobi T. Trajectories Of Perceived Social Support in Acute Coronary Syndrome. Quality of Life Research, 2019; 1-12

Sajobi TT, Wang M, Awosoga O, Santana M, Southern D, Liang Z, Galbraith D, Wilton SB, Quan H, Graham MM, James MT, Ghali WA, Knudtson ML, Norris C, for the APPROACH investigators. Trajectories of health-related quality of life in coronary artery disease. Circ Cardiovasc Qual Outcomes 2018; e003661

Chew DS, Wilton SB, Kavanagh K, Vaid HM, Southern DA, Ellis L, Howarth AG, White JA, Exner DV. Fragmented QRS complexes after acute myocardial infarction are independently associated with unfavorable left ventricular remodeling. Journal of Electrocardiology 51 (4), 607-612.

Southern DA, James MT, Wilton SB, DeKoning L, Quan H, Kundtson ML, Ghali WA. Expanding the impact of a longstanding Canadian cardiac registry through data linkage: challenges and opportunities. International Journal of Population Data Science.

McRae A, Graham M, Abedin T, Ji Y, Yang H, Wang D, Southern D, Andruchow J, Lang E, Innes G, Seiden-Long I, DeKoning L, Kavsak P. Sex-specific, high-sensitivity cardiac troponin T cut-off concentrations for ruling out acute myocardial infarction with a single measurement. CJEM. 2019 Jan;21(1):26-33.

Kissel CK, Chen G, Southern DA, Galbraith PD, Anderson TJ; APPROACH investigators. Impact of clinical presentation and presence of coronary sclerosis on long-term outcome of patients with non-obstructive coronary artery disease. BMC Cardiovasc Disord. 2018 Aug 22;18(1):173.

Chiu M, Miller R, Barry R, Li B, Har B, Wilton S, Knudtson M, Howlett J, James M. Kidney Function, ACE-inhibitor/angiotensin Receptor Blocker Use, and Survival Following Hospitalization For Heart Failure: A Cohort Study. Can J Kidney Health Dis. 2018; Oct 15; 5.

Grodecki K, Huczek Z, Scisło P, Kowara M, Roubín SR, D'Ascenzo F, Assi EA, Henriques JPS, Saucedo J, González-Juanatey JR, Wilton SB, Kikkert WJ, Nuñez-Gil I, Ariza-Sole A, Song X, Alexopoulos D, Liebetrau C, Kawaj Ti, Morett Ci, Nie S-P, Fujii T, Correia LCL, Kawashiri M, Acuña JMG, Southern D, Alfonso E, Terol B, Garay A, Zhang D, Chen Y, Xanthopoulou, Osman N, Möllmann H, Shiomi H, Giordana F, Scarano S, Gaita F, Wang X, Yan Y, Fan J-Y, Ikari Y, Nakahashi T, Sakata K, Yamagishi M, Kalpak O, Kedev S, Opolski G, Filipiak KJ. Gender-related differences in post-discharge bleeding among patients with acute coronary syndrome on dual antiplatelet therapy: A BleeMACS sub-study. Thrombosis research, Aug 2018 168: 156-163.

Garay A, Ariza-Solé A, Formiga F, Raposeiras-Roubín S, Abu-Assi E, Sánchez-Salado JC, Lorente V, Alegre O, Henriques JPS, D'Ascenzo F, Saucedo J, González-Juanatey JR, Wilton SB, Kikkert WJ, Nuñez-Gil I, Song X, Alexopoulos D, Liebetrau C, Kawaji T, Moretti C, Huczek Z, Nie S-P, Fujii T, Correia L, Kawashiri M, García-Acuña JM, Southern D, Alfonso E, Terol B, Zhang D, Chen Y, Xanthopoulou I, Osman N, Möllmann H, Shiomi H, Giordana F, Gaita F, Kowara M, Filipiak K, Wang X, Yan Y, Fan J-Y, Ikari Y, Nakahashi T, Sakata K, Yamagishi M, Kalpak O, Kedev S, Cequier A. Prediction of post-discharge bleeding in elderly patients with acute coronary syndromes: insights from the BleeMACS registry. Thrombosis and haemostasis, 2018 118(5):929-938.

D’Ascenzo F, Celentani D, Brustio A, Grosso A, Raposeiras-Roubín S, Abu-Assi E, Henriques JPS, Saucedo J, González-Juanatey JR, Wilton SB, Kikkert WJ, Nuñez-Gil I, Ariza-Sole A, Song X, Alexopoulos D, Liebetrau C, Kawaji T, Huczek Z, Nie S-P, Fujii T, Correia L, Kawashiri M, García-Acuña JM, Southern D, Alfonso E, Terol B, Garay A, Zhang D, Chen Y, Xanthopoulou I, Osman N, Möllmann H, Shiomi H, Kowara M, Filipiak K, Wang X, Yan Y, Fan J-Y, Ikari Y, Nakahayshi T, Sakata K, Yamagishi M, Kalpak O, Kedev S, Moretti C, D’Amico M, Gaita F. Association of Beta-Blockers with Survival on Patients Presenting with ACS Treated with PCI: A Propensity Score Analysis from the BleeMACS Registry. American Journal of Cardiovascular Drugs, Aug 2018 18(4): 299-309.

Raposeiras-Roubín S, Faxén J, Íñiguez-Romo A, Henriques JPS, D'Ascenzo F, Saucedo J, Szummer K, Jernberg T, James SK, Juanatey JRG, Wilton SB, Kikkert WJ, Nuñez-Gil I, Ariza-Sole A, Song X, Alexopoulos D, Liebetrau C, Kawaji T, Moretti C, Huczek Z, Nie S-P, Fujii T, Correia L, Kawashiri M, Caneiro-Queija B, Cobas-Paz R, Acuña JMG, Southern D, Alfonso E, Terol B, Garay A, Zhang D, Chen Y, Xanthopoulou I, Osman N, Möllmann H, Shiomi H, Giordana F, Gaita F, Kowara M, Wang KFX, Yan Y, Fan J-Y, Ikari Y, Nakahayshi T, Sakata K, Yamagishi M, Kalpak O, Kedev S, Rivera-Asenjo D, Abu-Assi E. Development and external validation of a post-discharge bleeding risk score in patients with acute coronary syndrome: The BleeMACS score. International Journal of Cardiology 2018 254, 10-15.

Kurich T, Lasiuk GC, Norris CM. Acute Coronary Syndromes Symptom Presentation Among Persons of South Asian Descent: A Comprehensive literature Review. Canadian Journal of Cardiovascular Nursing. 2017; 27 (1)

Miller RJ, Howlett JG, Chiu MH, Southern DA, Knudtson M, Wilton SB. Relationships among achieved heart rate, beta-blocker dose and long-term outcomes in patients with heart failure with atrial fibrillation. Open Heart 2017;3:e000520.

Iannaccone, M., D´Ascenzo, F., De Filippo, O. Gagliardi M, Southern DA, Raposeiras-Rubin S, Abu-Assis E, Henriques JPS, Saucedo J, Gonzalez-Juanatey JR, Wilton SB et al. Treatment of Acute Coronary Syndrome in patients with Malignancy: a BleeMACS sub-study. Am J Cardiovasc Drugs 2017. 17(1): 61-71.

McRae AD, Innes G, Graham MM, Lang E, Andruchow JE, Yang H, Ji Y, Vatanpour S, Southern DA, Wang D, Seiden-Long I, DeKoning L, Kavsak P. Comparative evaluation of 2-hour rapid diagnostic algorithms for acute myocardial infarction using high-sensitivity cardiac Troponin T. CanJCardiol published Online May3, 2017.

Brinkert M, Southern DA, James MT, Knudtson ML, Anderson TJ, Charbonneau F. Incidence and prognostic implications of late bleeding after myocardial infarction or unstable angina according to treatment strategy. CanJCardiol published Online May 5, 2017.

Abdi-Ali A, Miller RJH, Southern D, Zhang M, Mikami Y, Knudtson ML, Heydari B, Howarth AG, Lydell CP, James MT, Wilton SB, White J. LV Mass Independently Predicts Mortality and Need for Future Revascularization in Patients Undergoing Diagnostic Coronary Angiography. JACC Cardiovasc Imaging 2017 July.

Quadri G1, D Ascenzo F, Moretti C, D'Amico M, Raposeiras-Roubín S, Abu-Assi E, Henriques JP, Saucedo J, González-Juanatey JR, Wilton SB, Kikkert WJ, Nuñez-Gil I, Ariza-Sole A, Song X, Alexopoulos D, Liebetrau C, Kawaji T, Huczek Z, Nie SP, Fujii T, Correia L, Kawashiri MA, García-Acuña JM, Southern D, Alfonso E, Terol B, Garay A, Zhang D, Chen Y, Xanthopoulou I, Osman N, Möllmann H, Shiomi H, Omedè P, Montefusco A, Giordana F, Scarano S, Kowara M, Filipiak K, Wang X, Yan Y, Fan JY, Ikari Y, Nakahashi T, Sakata K, Yamagishi M, Kalpak O, Kedev S, Varbella F, Gaita F. Complete or incomplete coronary revascularization in patients with myocardial infarction and multivessel disease. A propensity score analysis from the "real life" BleeMACS (Bleeding complications in a Multicenter registry of patients discharged with diagnosis of Acute Coronary Syndrome) registry. EuroIntervention. 2017. pii: EIJ-D-16-00350. doi: 10.4244/EIJ-D-16-00350.

Wilson T, Miller J, Teare S, Penman C, Pearson W, Marlett NJ, Shklarov S, Galbraith PD, Southern DA, Knudtson ML, Norris CM, James MT, Wilton SB. Patient perspectives on engagement in decision-making in early management of non-ST elevation acute coronary syndrome: a qualitative study. BMC Medical Informatics and Decision Making 2017 17 (1), 153.

Shavadia JS, Southern DA, James MT, Welsh RC, Bainey KR. Kidney Function Modifies the Selection of Treatment Strategies and Long-term Survival in Stable Ischemic Heart Disease: Insights from the Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease (APPROACH) Registry. Eur Heart J Qual Care Clin Outcomes. 2017 Nov 2.

Berry TR, Curting KD, Courneya KS, McGannon KR, Norris CM, Rodgers WM, Spence JC. Heart disease and breast cancer perceptions: Ethnic differences and relationship to attentional bias. Health Psychology Open July-December 2016 3: 2055102916657673, first published on July 4, 2016 doi:10.1177/2055102916657673

Nagendran J, Moore MD, Norris CM*, Khani-Hanjani A, Mulled JC, Kim DH, Nagendran J. Is recipient BMI a risk factor for adverse long-term survival post-cardiac transplantation? International Journal of Obesity, 2016 APR 40(4) 721-4

Pelletier R, Khan NA, Cox J, Daskalopoulou SS, Eisenberg MJ, Bacon AL, Lavoie KL, Daskupta K, Rabi D, Humphries KH, Norris CM, Thanassoulis G, Behlouli H, Pilote L for the GENESIS-PRAXY Investigators Sex or Gender: Which predicts outcomes after acute coronary syndrome in the young? Journal of the American College of Cardiology. 67(2):127-35, 2016 Jan 19.

Li G , Sajobi TT , Menon BK , Korngut L , Lowerison M , James M , Wilton SB , Williamson T , Gill S, Drogos LL , Smith EE , Vohra S , Hill MD , Thabane L , 2016 Symposium on Registry-Based Randomized Controlled Trials in Calgary. (2016). Registry-based randomized controlled trials: advantages, challenges and areas for future research. Journal of clinical epidemiology. doi: 10.1016/j.jclin: X.

Cox JL , Dai S , Gong Y , McKelvie R , McMurtry MS , Oakes GH , Skanes A , Verma A , Wilton SB , Wyse DG. (2016). The Development and Feasibility Assessment of Canadian Quality Indicators for Atrial Fibrillation. The Canadian journal of cardiology. 32(12): 1566-69.

Gili S , D'Ascenzo F , Lococo MF , Moretti C , Gaita F , Raposeiras-Roubín S , Abu-Assi E , Henriques JP , Saucedo J , González-Juanatey JR , Wilton SB , Kikkert WJ , Nuñez-Gil I , Ariza-Sole A , Song X , Alexopoulos D , Liebetrau C , Kawaji T , Huczek Z , Nie SP , Fujii T , Correia L , Kawashiri MA , García-Acuña JM , Southern D , Alfonso E , Terol B , Garay A , Zhang D , Chen Y , Xanthopoulou I , Osman N , Möllmann H , Shiomi H , Scarano S , Kowara M , Filipiak K , Wang X , Yan Y , Fan JY , Ikari Y , Nakahashi T , Sakata K , Yamagishi M , Kalpak O , Kedev S. (2016). Impact of blood transfusion on in-hospital myocardial infarctions according to patterns of acute coronary syndrome: Insights from the BleeMACS registry. International journal of cardiology. 221: 364-370.

Giordana F , Montefusco A , D'Ascenzo F , Moretti C , Scarano S , Abu-Assi E , Raposeiras-Roubín S, Henriques JP , Saucedo J , González-Juanatey JR , Wilton SB , Kikkert WJ , Nuñez-Gil I , Ariza-Sole A , Song X , Alexopoulos D , Liebetrau C , Kawaji T , Huczek Z , Nie SP , Fujii T , Correia L , Kawashiri MA , García-Acuña JM , Southern D , Alfonso E , Terol B , Garay A , Zhang D , Chen Y , Xanthopoulou I, Osman N , Möllmann H , Shiomi H , Kowara M , Filipiak K , Wang X , Yan Y , Fan JY , Ikari Y , Nakahayshi T , Sakata K , Yamagishi M , Kalpak O , Kedev S , Gaita F. (2016). Safety and effectiveness of the new P2Y12r inhibitor agents vs clopidogrel in ACS patients according to the geographic area: East Asia vs Europe. International journal of cardiology. 220: 488-95.

Miller RJH, Howlett JG, Chiu MH, Southern DA, Knudtson ML, Wilton SB. Relationships Among Achieved Heart Rate, Beta-Blocker Dose and Long-term Outcomes in Heart Failure Patients with Atrial Fibrillation. Open Heart 2016;3:e000520. doi:10.1136/openhrt-2016- 000520.

Yan Y , Wang X , Fan JY , Nie SP , Raposeiras-Roubín S , Abu-Assi E , Henriques JP , D'Ascenzo F, Saucedo J , González-Juanatey JR , Wilton SB , Kikkert WJ , Nuñez-Gil I , Ariza-Sole A , Song XT, Alexopoulos D , Liebetrau C , Kawaji T , Moretti C , Huczek Z , Fujii T , Correia LC , Kawashiri MA , Kedev S. (2016). Impact of concomitant use of proton pump inhibitors and clopidogrel or ticagrelor on clinical outcomes in patients with acute coronary syndrome. Journal of geriatric cardiology : JGC. 13(3): 209-17.

Gerling ME, James MT, Wilton SB, Naugler C, Southern DA, Galbraith PD, Knudtson M, de Koning L. Serum Total 25-OH Vitamin D Adds Little Prognostic Value in Patients Undergoing Coronary Catheterization. J Am Heart Assoc 2016;5: e004289, originally published October 21, 2016. doi: 10.1161/JAHA.116.004289

Wijeysundera HC, Sidhu MS, Bennell MC, Qiu F, Ko DT, Knudtson ML, Tu JV, Boden WE. Predictors of Initial Revascularization Versus Medical Therapy Alone in Patients With Non-ST-Segment-Elevation Acute Coronary Syndrome Undergoing an Invasive Strategy. Circ Cardiovasc Interv. 2016 Jul;9(7). pii: e003592. doi: 10.1161/CIRCINTERVENTIONS.115.003592.

O'Neill DE, Knudtson ML, Kieser TM, Graham MM. Considerations in Cardiac Revascularization for the Elderly Patient: Age Isn't Everything. Can J Cardiol. 2016 Sep;32(9):1132-9. doi: 10.1016/j.cjca.2016.05.003. Epub 2016 May 7. Review.

Wolff R, Fefer P, Knudtson ML, Cheema AN, Galbraith PD, Sparkes JD, Wright GA, Wijeysundera HC, Strauss BH. Gender differences in the prevalence and treatment of coronary chronic total occlusions. Catheter Cardiovasc Interv. 2016 May;87(6):1063-70. doi: 10.1002/ccd.26330. Epub 2015 Nov 25.

James MT, Wilton SB, Clement FM, Ghali WA, Knudtson ML, Tan Z, Tonelli M, Hemmelgarn BR, Norris CM, the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) and Alberta Kidney Disease Network (AKDN) Investigators. Kidney Function Does Not Modify the Favorable Quality of Life Changes Associated With Revascularization for Coronary Artery Disease: Cohort Study. J Am Heart Assoc. 2016; 5: e003642 doi: 10.1161/JAHA.116.003642

Senaratne J, Norris CM, Graham MM, Galbraith D, Nagendran J, Freed D, VanDiepen S. Clinical and angiographic outcomes associated with surgical revascularization of angiographically borderline 50-69% coronary artery stenoses. Eur J Cardiothorac Surg 2016, Jan29;

Abdi_Ali A, Shaheen A, Southern DA, Zhang M, Knudtson ML, White J, Wilton SB. Relation between family history of premature CAD and the risk of death in patients with coronary artery disease. Am J Cardiol. 2016 Feb 1;117(3):353-8.

D’Ascnezo F, Abu-Assi E, Raposeiras-Roubin S, Henriques JPS, Wilton SB, Kikkert WJ, Nunex-Gil I, Ariza-Sole A, Song X, Alexopoulos D, Liebetrau C, Kawaji T, Moretti C, Huczek Z, Nie S_P, Fujii T, Correia LC, Kawashiri M, Garcia-Acuna JM, Southern D, Alfonso E, Terol B, Garay A, Zhang D, Chen Y, Xanthopoulou I, Osman N, Mollmann H, Shiomi H, Giordana F, Scarano S, Gaita F, Kowara M, Filipial KJ, Wang X, Yan Y, Fan J-Y, Ikari Y, Naakahayshi T, Sakata K, Yamagishi M, Kalpak O, Kedev S. BleeMACS: rationale and design of the study. J Cardiovasc Med 2016, 17:000-000

Fabreau GE, Leung AA, Southern DA, James MT, Knudtson ML, Ghali WA, Ayanian JZ.. Area median income and metropolitan vs non-metropolitan location of care for Acute Coronary Syndromes: A complex interaction of social determinants. J Am Heart Assoc. 2016;5:e002447

Van Diepen S, Lin M, Bakal JA, McAlister FA, Kaul P, Katz JN, Fordyce CB, Southern DA, Graham MM, Wilton SB, Newby LK, Granger CB, Ezekowitz JA. Do stable non-ST-segment elevation acute coronary syndromes require admission to coronary care units? Am Heart J. 2016 May;175:184-92.

Berresheim M, Barry AR, Norris CM, Koshman SL, Nagendran J, Pearson GJ. Real-life practice in the management of new-onset postoperative atrial fibrillation early after cardiac surgery. Curr Res Cardiol 2015;2(2):73-76.

Armstrong MJ, Sigal RJ, Arena R, Hauer TL, Austford LD, Stone JA, Aggarwal S, Martin BJ. Cardiac Rehabilitation Completion is Associated with Reduced Mortality in Diabetic Patients with Coronary Artery Disease. Diabetologia. April 2015, Volume 58, Issue 4, pp 691-698

Southern DA, Doherty C, De Souza MA, Quan H, Harrop AR, Nickerson D, Rabi D. Charts versus Discharge ICD-10 Coding for Sternal Wound Infection Following Coronary Artery Bypass Grafting. Perspectives in Health Inf Manag, 2015, Jul 1; 12:1e.

Hui Wkk, O’Brien DG, Brass NS, Cheung PK, Chan MCY, Leung RCM, Tyrrell BD, Bundhoo S, Pongnonthachai P, Galbraith PD, Ranjbar K, Dorsch M, MacArthur R, Klinke WP. Thirty years of standalone percutaneous coronary interventions: A 23,261 case experience from a Canadian tertiary referral centre. Curr Res Cardiol 2015:2(4):183-187.

Leggett LE, Hauer T, Martin BJ, Manns B, Aggarwal S, Arena R, Austford LD, Meldrum D, Ghali W, Knudtson ML, Norris CM, Stone JA, Clement F. Optimizing value from cardiac rehabilitation: A cost-utility analysis comparing age, sex, and clinical subgroups. Mayo Clinic Proceedings, July 2015, doi: 10.1016/j.mayocp.2015.05.015

Shavadia J, Norris CM, Graham MM, Subodh V, Imtiaz A, Bainey KR. Symptomatic graft failure and impact on clinical outcome after coronary artery bypass grafting surgery: Results from the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease registry. American Heart Journal , Volume 169 , Issue 6 , 833 - 840, Published Online: March 14, 2015. doi: http://dx.doi.org/10.1016/j.ahj.2015.02.022

Leung KCW, Pannu N, Tan Z, Ghali WA, Knudtson ML, Hemmelgarn BR, Tonelli M, James M for the APPROACH and AKDN Investigators. Contrast associated AKI and use of cardiovascular medications after acute coronary syndrome. CJASN 2014; 9(11) 1840-1848; published ahead of print October 15, 2014, doi:10.2215/CJN.03460414

Sebastianski M, Narasimhan S, Graham MM, Toleva O, Shavadia J, Abualnaja S, Tsuyuki RT, McMurtry MS. Usefulness of the ankle-brachial index to predict high coronary SYNTAX scores, myocardium at risk, and incomplete coronary revascularization. Am J Cardiol. 2014 Dec 1;114(11):1745-9. doi: 10.1016/j.amjcard.2014.09.010. Epub 2014 Sep 16.

Devereaux PJ, Mrkobrada M, Sessler DI, Leslie K, Alonso-Coello P, Kurz A, Villar JC, Sigamani A, Biccard BM, Meyhoff CS, Parlow JL, Guyatt G, Robinson A, Garg AX, Rodseth RN, Botto F, Lurati Buse G, Xavier D, Chan MT, Tiboni M, Cook D, Kumar PA, Forget P, Malaga G, Fleischmann E, Amir M, Eikelboom J, Mizera R, Torres D, Wang CY, VanHelder T, Paniagua P, Berwanger O, Srinathan S, Graham M, Pasin L, Le Manach Y, Gao P, Pogue J, Whitlock R, Lamy A, Kearon C, Baigent C, Chow C, Pettit S, Chrolavicius S, Yusuf S; POISE-2 Investigators. Aspirin in patients undergoing noncardiac surgery. N Engl J Med. 2014 Apr 17;370(16):1494-503. doi: 10.1056/NEJMoa1401105. Epub 2014 Mar 31.

Devereaux PJ, Sessler DI, Leslie K, Kurz A, Mrkobrada M, Alonso-Coello P, Villar JC, Sigamani A, Biccard BM, Meyhoff CS, Parlow JL, Guyatt G, Robinson A, Garg AX, Rodseth RN, Botto F, Lurati Buse G, Xavier D, Chan MT, Tiboni M, Cook D, Kumar PA, Forget P, Malaga G, Fleischmann E, Amir M, Eikelboom J, Mizera R, Torres D, Wang CY, Vanhelder T, Paniagua P, Berwanger O, Srinathan S, Graham M, Pasin L, Le Manach Y, Gao P, Pogue J, Whitlock R, Lamy A, Kearon C, Chow C, Pettit S, Chrolavicius S, Yusuf S; POISE-2 Investigators. Clonidine in patients undergoing noncardiac surgery. N Engl J Med. 2014 Apr 17;370(16):1504-13. doi: 10.1056/NEJMoa1401106. Epub 2014 Mar 31.

Botto F, Alonso-Coello P, Chan MT, Villar JC, Xavier D, Srinathan S, Guyatt G, Cruz P, Graham M, Wang CY, Berwanger O, Pearse RM, Biccard BM, Abraham V, Malaga G, Hillis GS, Rodseth RN, Cook D, Polanczyk CA, Szczeklik W, Sessler DI, Sheth T, Ackland GL, Leuwer M, Garg AX, Lemanach Y, Pettit S, Heels-Ansdell D, Luratibuse G, Walsh M, Sapsford R, Schünemann HJ, Kurz A, Thomas S, Mrkobrada M, Thabane L, Gerstein H, Paniagua P, Nagele P, Raina P, Yusuf S, Devereaux PJ, Devereaux PJ, Sessler DI, Walsh M, Guyatt G, McQueen MJ, Bhandari M, Cook D, Bosch J, Buckley N, Yusuf S, Chow CK, Hillis GS, Halliwell R, Li S, Lee VW, Mooney J, Polanczyk CA, Furtado MV, Berwanger O, Suzumura E, Santucci E, Leite K, Santo JA, Jardim CA, Cavalcanti AB, Guimaraes HP, Jacka MJ, Graham M, McAlister F, McMurtry S, Townsend D, Pannu N, Bagshaw S, Bessissow A, Bhandari M, Duceppe E, Eikelboom J, Ganame J, Hankinson J, Hill S, Jolly S, Lamy A, Ling E, Magloire P, Pare G, Reddy D, Szalay D, Tittley J, Weitz J, Whitlock R, Darvish-Kazim S, Debeer J, Kavsak P, Kearon C, Mizera R, O'Donnell M, McQueen M, Pinthus J, Ribas S, Simunovic M, Tandon V, Vanhelder T, Winemaker M, Gerstein H, McDonald S, O'Bryne P, Patel A, Paul J, Punthakee Z, Raymer K, Salehian O, Spencer F, Walter S, Worster A, Adili A, Clase C, Cook D, Crowther M, Douketis J, Gangji A, Jackson P, Lim W, Lovrics P, Mazzadi S, Orovan W, Rudkowski J, Soth M, Tiboni M, Acedillo R, Garg A, Hildebrand A, Lam N, Macneil D, Mrkobrada M, Roshanov PS, Srinathan SK, Ramsey C, John PS, Thorlacius L, Siddiqui FS, Grocott HP, McKay A, Lee TW, Amadeo R, Funk D, McDonald H, Zacharias J, Villar JC, Cortés OL, Chaparro MS, Vásquez S, Castañeda A, Ferreira S, Coriat P, Monneret D, Goarin JP, Esteve CI, Royer C, Daas G, Chan MT, Choi GY, Gin T, Lit LC, Xavier D, Sigamani A, Faruqui A, Dhanpal R, Almeida S, Cherian J, Furruqh S, Abraham V, Afzal L, George P, Mala S, Schünemann H, Muti P, Vizza E, Wang CY, Ong GS, Mansor M, Tan AS, Shariffuddin II, Vasanthan V, Hashim NH, Undok AW, Ki U, Lai HY, Ahmad WA, Razack AH, Malaga G, Valderrama-Victoria V, Loza-Herrera JD, De Los Angeles Lazo M, Rotta-Rotta A, Szczeklik W, Sokolowska B, Musial J, Gorka J, Iwaszczuk P, Kozka M, Chwala M, Raczek M, Mrowiecki T, Kaczmarek B, Biccard B, Cassimjee H, Gopalan D, Kisten T, Mugabi A, Naidoo P, Naidoo R, Rodseth R, Skinner D, Torborg A, Paniagua P, Urrutia G, Maestre ML, Santaló M, Gonzalez R, Font A, Martínez C, Pelaez X, De Antonio M, Villamor JM, García JA, Ferré MJ, Popova E, Alonso-Coello P, Garutti I, Cruz P, Fernández C, Palencia M, Díaz S, Del Castillo T, Varela A, de Miguel A, Muñoz M, Piñeiro P, Cusati G, Del Barrio M, Membrillo MJ, Orozco D, Reyes F, Sapsford RJ, Barth J, Scott J, Hall A, Howell S, Lobley M, Woods J, Howard S, Fletcher J, Dewhirst N, Williams C, Rushton A, Welters I, Leuwer M, Pearse R, Ackland G, Khan A, Niebrzegowska E, Benton S, Wragg A, Archbold A, Smith A, McAlees E, Ramballi C, Macdonald N, Januszewska M, Stephens R, Reyes A, Paredes LG, Sultan P, Cain D, Whittle J, Del Arroyo AG, Sessler DI, Kurz A, Sun Z, Finnegan PS, Egan C, Honar H, Shahinyan A, Panjasawatwong K, Fu AY, Wang S, Reineks E, Nagele P, Blood J, Kalin M, Gibson D, Wildes T; Vascular events In noncardiac Surgery patIents cOhort evaluatioN (VISION) Writing Group, on behalf of The Vascular events In noncardiac Surgery patIents cOhort evaluatioN (VISION) Investigators; Appendix 1. The Vascular events In noncardiac Surgery patIents cOhort evaluatioN (VISION) Study Investigators Writing Group; Appendix 2. The Vascular events In noncardiac Surgery patIents cOhort evaluatioN Operations Committee; Vascular events In noncardiac Surgery patIents cOhort evaluatioN VISION Study Investigators. Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes. Anesthesiology. 2014 Mar;120(3):564-78. doi: 10.1097/ALN.0000000000000113.

Todd RA, Lewin AM, Bresee LC, Southern D, Rabi DM. Coronary artery disease in adults with schizophrenia: Anatomy, treatment and outcomes. IJC Heart & Vessels 2014. http://dx.doi.org/10.1016/j.ijchv.2014.06.009

Curran HJ, Hubacek J, Southern D, Galbraith D, Knudtson ML, Ghali WA, Graham MM. The effect of a regional care model on cardiac catheterization rates in patients with Acute Coronary Syndromes. BMC Health Services Research 2014, 14:550. doi: 10.1186/s12913-014-0550-0.

van Diepen S, Graham MM, Nagendran J, Norris CM. Predicting cardiovascular intensive care unit readmission after cardiac surgery: derivation and validation of the Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease (APPROACH) cardiovascular intensive care unit clinical prediction model from a registry cohort of 10799 surgical cases. Critical Care. 2014, 18:651

Doherty C, Nickerson D, Southern DA, Kieser T, Appoo J, Dawes J, deSouza MA, Harrop AR, Rabi D for the APPROACH Investigators. Trends in post-coronary artery bypass graft sternal wound dehiscence in a provincial population. Can J Plast Surg. 2014; 22(3):196-200.

Bressee LC, Knudtson ML, Zhang J, Crowshoe L, Ahmed SB, Tonelli M, Ghali WA, Quan H, Manns B, Fabreau G, Hemmelgarn B for the AKDN and APPROACH investigators. Access to and outcomes after coronary angiography for First Nations people with acute myocardial infarction. CMAJ. 2014; 186(10): E372–E380. doi: 10.1503/cmaj.131667

Hammal F, Ezekowitz JA, Norris CM, Wild TC, Finegan BA. Smoking status and survival: impact on mortality of continuing to smoke one year after the angiographic diagnosis of coronary artery disease, a prospective cohort study. BMC Cardiovascular Disorders 2014, 14:133

Southern DA, Ngo J, Martin BJ, Galbraith PD, Knudtson ML, Ghali WA, James MT, Wilton SB. Characterizing types of readmission after acute coronary syndrome hospitalization: Implications for quality reporting. J Am Heart Assoc. 2014;3:e001046

Barry AR, Koshman SL, Norris CM, Ross DB, Pearson GJ. Evaluation of preventive cardiovascular pharmacotherapy after coronary artery bypass graft surgery. Pharmacotherapy. 2014 May;34(5):464-72. PMID:24877186

O'Neill DE, Southern DA, O'Neill BJ, McMurtry MS, Graham MM. Weekend compared with weekday presentation does not affect outcomes of patients presenting with non-ST elevation acute coronary syndrome. Eur Heart J Acute Cardiovasc Care. 2014 Jun;3(2):99-104. doi: 10.1177/2048872613510086. Epub 2013 Oct 16.PMID: 24585942

Nagendran J, Norris CM, Appoo JJ, Ross DB, Nagendran J; APPROACH Investigators. Left ventricular end-diastolic pressure predicts survival in coronary artery bypass graft surgery patients. Annals of Thoracic Surgery 2014; 97(4): p 1343-1347 doi: 10.1016/j.athoracsur.2013.10.047

Wijeysundera HC, Norris CM, Fefer P, Galbraith PD, Knudtson ML, Wolfe R, Wright GA, Strauss B, Ko DT. Relationship between initial treatment strategy and quality of life in patients with coronary chronic total occlusions. EuroIntervention 2014; 9(10):p1165-72. https://eurointervention.pcronline.com/article/relationship-between-initial-treatment-strategy-and-quality-of-life-in-patients-with-coronary-chronic-total-occlusions

Martin BJ, Chen G, Graham MM, Quan H. Coding of obesity in administrative hospital discharge abstract data: accuracy and impact for future research studies. BMC Health Serv Res. 2014 Feb 13;14:70. doi: 10.1186/1472-6963-14-70. PMID:24524687

Fabreau GE, Leung AA, Southern DA, Knudtson ML, McWilliams JM, Ayanian JZ, Ghali WA. Sex, socioeconomic status, access to cardiac catheterization, and outcomes for acute coronary syndromes in the context of universal healthcare coverage. Circulation Outcomes, circoutcomes.114.001021

Mitchell LB, Southern DA, Galbraith D, Ghali WA, Knudtson ML, Wilton SB. Prediction of stroke or TIA in patients without atrial fibrillation using CHADS2 and CHA2DS2-VASc scores. Heart Published Online First: May 23, 2014. doi:10.1136/ heartjnl-2013-305303

Kaila KS, Norris CM, Graham MM, Ali I, Bainey KR. Long-term Survival with Revascularization in South Asians Admitted with an Acute Coronary Syndrome (From the Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease [APPROACH] Registry). 10.1016/j.amjcard.2014.04.051. doi: 10.1016/j.amjcard.2014.04.051. Epub 2014 May 16.

Gyenes G, Norris CM, Graham MM; APPROACH Investigators. Percutaneous revascularization improves outcomes in patients with prior coronary artery bypass surgery. Catheter Cardiovasc Interv. 2013. 82(3):E148-54. doi: 10.1002/ccd.24711. Epub 2012 Dec 3.

Colbert JD, Martin BJ, Haykowsky MJ, Hauer TL, Austford LD, Arena RA, Knudtson ML, Meldrum DAN, Aggarwal SG, Stone JA. Cardiac rehabilitation referral, attendance and mortality in women. J Am Coll Cardiol. 2013;61(10_S):. doi:10.1016/S0735-1097(13)61414-X.

Izadnegahdar M, Norris CM, Kaul P, Pilote L, Humphries KH. Basis for Sex-Dependent Outcomes in Acute Coronary Syndrome. Can J Cardiol. 2014 Jul;30(7):713-20. doi: 10.1016/j.cjca.2013.08.020.

Nagendran J, Norris CM, Appoo JJ, Ross DB, Nagendran J. Coronary revascularization for patients with severe left ventricular dysfunction. Ann Thorac Surg. 2013 Dec;96(6):2038-44. doi: 10.1016/j.athoracsur.2013.06.052. Epub 2013 Aug 20. PMID:23968761

Khan N , Daskalopoulou S , Karp I, Eisenberg M, Pelletier R , Avgil TM, Dasgupta K, Norris CM, Pilote L. Sex Differences in Acute Coronary Syndrome Symptom Presentation in the Young. JAMA Archives of Internal Medicine 2013;173(20):1863-71.

Veronovici NR, Lasiuk G, Remple G, Norris CM. Discharge Education to Promote Self-Management Following Cardiovascular Surgery: An Integrative Review. European Journal of Cardiovascular Nursing published online 15Sept2013)

James MT, Tonelli M, Ghali WA, Knudtson ML, Faris P, Manns BJ, Pannu N, Galbraith PD, Hemmelgarn BR for the APPROACH and AKDN Investigators. Renal outcomes associated with invasive versus conservative management of ACS: propensity-matched cohort study. BMJ 2013:347.=:f4151 dol: 10.1136/bmj.f1451 (Published 5Jul2013)

Kieser KM, Curran H, Rose MS, Norris CM, Graham MM. Arterial grafts balance survival between incomplete and complete revascularization: A series of 1000 consecutive coronary artery bypass graft patients with 98% arterial grafts. J of Thoracic and CV Surgery 2013;147;1 p75 - 84)

Martin BJ, Arena R, Haykowsky M, Hauer T, Austford LD, Knudtson M, Aggarwal S, Stone JA for the APPROACH Investigators. Cardiovascular fitness and mortality after contemporary cardiac rehabilitation. Mayo Clin Proc. 2013 May;88(5):455-63. doi: 10.1016/j.mayocp.2013.02.013.

Graham MM, Galbraith PD, O'Neill D, Rolfson DB, Dando C, Norris CM. Frailty and Outcome in Elderly Patients with Acute Coronary Syndrome. Can J Cardiol. Vol.29 2013 1610-1615

Leung AA, Southern DA, Galbraith PD, Knudtson ML, Philpott AC, Ghali WA. Time Dependency of Outcomes for Drug-Eluting vs. Bare-Metal Stents. Can J Cardiol. Vol.29 2013 1616-1622

Beck CA, Southern DA, Saitz R, Knudtson ML, Ghali WA. Alcohol and Drug Use Disorders among Patients with Myocardial Infarction: Associations with Disparities in Care and Mortality. PLoS ONE 8(9):e66551.doi:10.1371/journal.pone.0066551. 2013

Ouzounian M, Ghali W, Yip AM, Buth KJ, Humphries K, Stukel TA, Norris CM, Southern DA, Galbraith PD, Thompson CR, Abel J, Love MP, Hassan A, Hirsch GM. Determinants of Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting: An Interprovincial Comparison. Can J Cardiol. 2013 Aug 6. [Epub ahead of print].

Kaul P, Ezekowitz JA, Armstrong PW, Leung BK, Savu A, Welsh RC, Quan H, Knudtson ML, McAlister FA. Incidence of heart failure and mortality after acute coronary syndromes. AHJ. 2013 Jan 28. [Epub ahead of print].

James MT, Samuel SM, Manning MA, Tonelli M, Ghali WA, Faris P, Knudtson ML, Pannu N, Hemmelgarn BR. Contrast-Induced Acute Kidney Injury and Risk of Adverse Clinical Outcomes After Coronary Angiography: A Systematic Review and Meta-Analysis. Circ Cardiovasc Interv. 2013 Jan 15. [Epub ahead of print].

Martin BJ, Aggarwa SG, Stone JA, Hauer T, Austford LD, Knudtson ML for the APPROACH Investigators and Ross Arena. Obesity Negatively Impacts Aerobic Capacity Improvements Both Acutely and 1-Year Following Cardiac Rehabilitation. Obesity (2012) 20, 2377–2383. doi:10.1038/oby.2012.119

Mutsuga M, Quinonez LG, Mackie AS, Norris CM, Marchak EB, Rutledge JM, Rebeyka IM, Ross DB. Fast-track extubation after modified Fontan procedure. J Thorac Cardiovasc Surg. 2012;(144)3:547-52

Shearer K, Rempel G, Norris CM, & Magill-Evans J. (2011). "It's No Big Deal": Adolescents With Congenital Heart Disease. J Pediatr Nurs. 2012 Apr24 (Epub ahead of print).

Fech JC, Welsh R, Hegadoren KM, Norris CM. Caring for the radial artery post-angiogram: a pilot study on a comparison of three methods of compression. Eur J Cardiovasc Nurs. 2012; 11(1):44-50.

Patel AB, Waters NM, Blanchard IE, Doig CJ, Ghali WA. A validation of ground ambulance pre-hospital times modeled using geographic information systems. Int J Health Geogr. 2012 Oct

McMurtry MS, Southern DA, Lewin AM, Galbraith PD, Kaul P, Ghali WA, Knudtson ML, Graham MM. Recent Temporal Trends and Geographic Distribution of Cardiac Procedures in Alberta. Can J Cardiol. 2012 Aug 14. [Epub ahead of print]

Martin BJ, Hauer T, Arena R, Austford LD, Galbraith PD, Lewin AM, Knudtson ML, Ghali WA, Stone JA, Aggarwal SG. Cardiac rehabilitation attendance and outcomes in coronary artery disease patients. Circulation. 2012 Aug 7;126(6):677-87. doi: 10

Soon IS, Molodecky NA, Rabi DM, Ghali WA, Barkema HW, Kaplan GG. The relationship between urban environment and the inflammatory bowel diseases: a systematic review and meta-analysis. BMC Gastroenterol. 2012 May 24;12(1):51. [Epub ahead of print]

Feasby TE, Quan H, Tubman M, Pi D, Tinmouth A, So L, Ghali WA. Appropriateness of the use of intravenous immune globulin before and after the introduction of a utilization control program. Open Med. 2012;6(1):e28-34. Epub 2012 Mar 13.

King-Shier KM, Quan H, Mather C, Verhoef MJ, Knutson ML, Ghali WA. Understanding coronary artery disease patients' decisions regarding the use of chelation therapy for coronary artery disease: descriptive decision modeling. Int J Nurs Stud. 2012 Sep;49(9):1074-83. doi: 10.1016/j.ijnurstu.2012.03.011. Epub 2012 Apr 23.

Molodecky NA, Soon IS, Rabi DM, Ghali WA, Ferris M, Chernoff G, Benchimol EI, Panaccione R, Ghosh S, Barkema HW, Kaplan GG. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology. 2012 Jan;142(1):46-54.e42; quiz e30. Epub 2011 Oct 14. Review.

Rodondi N, Auer R, de Bosset Sulzer V, Ghali WA, Cornuz J. Atherosclerosis screening by noninvasive imaging for cardiovascular prevention: a systematic review. J Gen Intern Med. 2012 Feb;27(2):220-31. doi: 10.1007/s11606-011-1833-3. Epub 2011 Sep 1. Review.

Freiheit EA, Hogan DB, Eliasziw M, Patten SB, Demchuk AM, Faris P, Anderson T, Galbraith PD, Parboosingh JS, Ghali WA Knudtson ML, Maxwell CJ. A dynamic view of depressive symptoms and neurocognitive change among patients with coronary artery disease. Arch Gen Psychiatry 2012 69(3):244-255.

Bainey KR, Selzer F, Cohen HA, Marroquin OC, Holper EM, Graham MM, Williams DO, Faxon DP. Comparsion of three age groups regarding safety and efficacy of drug-eluting stents (from the National Heart, Lung and Blood Institute dynamic registry). Am J Cardiol. 2012 Jan;109(2):195-201.

Fefer P, Knudtson ML, Cheema AN, Galbraith PD, Osherov AB, Yalonetsky S, Gannot S, Samuel M, Weisbrod M, Bierstone D, Sparkes JD, Wright GA, Strauss BH. Current perspectives on coronary chronic total occlusions: the Canadian multicenter chronic total occlusions registry. J Am Coll Cardiol. 2012 Mar13; 59(11):991-7.

Patel AB, Quan H, Faris P, Knudtson ML, Traboulsi M, Li B, Ghali WA. Temporal Associations of Early Patient Transfers and Mortality with the Implementation of a Regional Myocardial Infarction Care Model. Can J Cardiol 2011;27:731-738. doi: 10.1016.cjca.2011.08.114.

Conly J, Clement FM, Tonelli M, Hemmelgarn BR, Klarenbach SW, Lloyd A, McAlister F, Grover S, Husereau D, Wiebe N, Manns BJ. The cost-effectiveness of low and high potency statins for patients at low cardiovascular risk. CMAJ. 2011 Nov 8;183(16):E1180-E1188. Epub 2011 Oct 11.

Graham MM, Ghali WA, Southern DA, Traboulsi M, Knudtson ML. Outcomes of after-hours versus regular working hours primary percutaneous coronary intervention for acute myocardial infarction. BMJ Qual Saf. 2011 Jan;20(1):60-67.

Dennis T Ko, Atzema CL, Donovan LR, Graham MM, Huynh T, So DY, Wang J, Wijeysundera HC, Tu JV. Rescue percutaneous coronary interventions for failed fibrinolytic therapy in ST-segment elevation myocardial infarction: A population-based study. Am Heart J. 2011 Apr;161(4):764-770.

Kavsak PA, Walsh M, Srinathan S, Thorlacius L, Buse GL, Botto F, Pettit S, McQueen MJ, Hill SA, Thomas S, Mrkobrada M, Pablo AC, Berwanger O, Biccard BM, Cembrowski G, Chan MTV, Chow CK, Miguel A, Garcia M, Graham MM, Jacka MJ, Kueh JH, Li SCH, Lit LCW, Martinez-Bru C, Naidoo P, Nagele P, Pearse RM, Rodseth RN, Sessler DI, Sigamani A, Wojciech S, Tiboni M, Villar JC, Wang CY, Xavier D, Devereaux PJ. High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: A prospective cohort study. Clinical Biochemistry. 2011 Aug;44(12):1021-1024.

Graham, MM. Enhancing the Framingham Risk Score for coronary heart disease by adding information on working hours. Evidence Based Med. 2011 Epub Oct 25.

Clement FM, Manns BJ, Brownell B, Faris PD, Graham MM, Humphries K, Love M, Knudtson ML, Ghali WA. A multi-region assessment of population rates of cardiac catheterization and yield of high-risk coronary artery disease. BMC Health Services Research. 2011 Nov;11:32.

Kaul P, Chang WC, Westerhout CM, Graham MM, Armstrong PW. Differences in admission rates and outcomes between men and women presenting to emergency departments with coronary syndromes. CMAJ 2011 Nov;177(10):1193-1199.

Clement FM, Ghali WA, Rinfret S, Manns BJ, APPROACH Investigators. Economic evaluation of increasing population rates of cardiac catheterization. BMC Health Serv Res 2011 Nov24;11:324.

Kieser TM, Lewin AM, Graham MM, Martin BJ, Galbraith PD, Rabi DM, Norris CM, Faris PD, Knudtson ML, Ghali WA; “APPROACH” Investigators. Outcomes associated with bilateral internal thoracic artery grafting: the importance of age. Ann Thorac Surg. 2011 Oct;92(4):1269-76.

Bainey KR, Norris CM, Gupta M, Southern D, Galbraith D, Knudtson ML, Graham MM. Altered health status and quality of life in South Asians with coronary artery disease. Am Heart J. 2011 Sep;162(3):501-6.

McMurtry MS, Lewin AM, Knudtson ML, Ghali WA, Galbraith PD, Schulte F, Norris CM, Graham MM. The Clinical Profile and Outcomes Associated With Coronary Collaterals in Patients With Coronary Artery Disease. Can J Cardiol. 2011 Jul 8. [Epub ahead of print].

Ko DT, Atzema CL, Donovan LR, Graham MM, Huynh T, So DY, Wang J, Wijeysundera HC, Tu JV. Rescue percutaneous coronary interventions for failed fibrinolytic therapy in ST-segment elevation myocardial infarction: a population-based study. Am Heart J. 2011 Apr;161(4):764-770.e1.

Lehr EJ, Wang PZ, Oreopoulos A, Kanji H, Norris C, Macarthur R. Midterm Outcomes and Quality of Life of Aortic Root Replacement: Mechanical vs Biological Conduits. Can J Cardiol. 2011 Mar-Apr;27(2):262.e15-20.

DA Southern, M Izadneghadar, KH Humphries, M Gao, F Wang, ML Knudtson, MM Graham, WA Ghali. Trends in wait times for cardiac revascularization. Can J Cardiol. 2011 Mar-Apr;27(2):262.e21-7.

Kaul P, McAlister FA, Ezekowitz JA, Bakal JA, Curtis LH, Quan H, Knudtson ML, Armstrong PW. Resource use in the last 6 months of life among patients with heart failure in Canada. Arch Intern Med. 2011 Feb 14;171(3):211-7. Epub 2010 Oct 11.

James MT, Ghali WA, Knudtson ML, Ravani P, Tonelli M, Faris PD, Pannu N, Manns BJ, Klarenbach SW, Hemmelgarn BR for the APPROACH Investigators. Associations between acute kidney injury and cardiovascular and renal outcomes after coronary angiography. CIRC 2011 Feb1;123(4):409-16. Epub Jan17.

Graham MM, Ghali WA, Southern DA, Traboulsi M, Knudtson ML, for the APPROACH Investigators. Outcomes of after-hours vs regular working hours primary PCI for AMI. BMJ Qual Saf 2011;20:60-67.

Alton GY, Rempel GR, Robertson CMT, Newburn-Cook CV, Norris CM. Functional outcomes after neonatal open heart surgery; Comparison of survivors of the norwood staged procedure and the arterial switch operation. Cardiol Young. 2010 Dec; 20(6):668-75.

Tardif JC, L'Allier PL, Grégoire J, Ibrahim R, McFadden G, Kostuk W, Knudtson M, Labinaz M, Waksman R, Pepine CJ, Macaulay C, Guertin MC, Lucas A. A randomized controlled, phase 2 trial of the viral serpin Serp-1 in patients with acute coronary syndromes undergoing percutaneous coronary intervention. Circ Cardiovasc Interv. 2010 Dec;3(6):543-8. Epub 2010 Nov 9.

Kaul P, McAlister FA, Ezekowitz JA, Bakal JA, Curtis LH, Quan H, Knudtson ML, Armstrong PW. Resource use in the last 6 months of life among patients with heart failure in Canada Arch Intern Med. 2011 Feb 14;171(3):211-7. Epub 2010 Oct 11.

Wijeysundera HC, Tomlinson G, Norris CM, Ghali WA, Ko DT, Krahn MD. Predicting EQ-5D Utility Scores from the Seattle Angina Questionnaire in Coronary Artery Disease: A Mapping Algorithm Using a Bayesian Framework. Med Decis Making. 2010 Dec 2. [Epub ahead of print].

Oreopoulos A, Kalantar-Zadeh K, McAlister FA, Ezekowitz JA, Fonarow GC, Johnson JA, Norris CM, Padwal RS. Comparison of direct body composition assessment methods in patients with heart failure. J Card Fail. 2010 Nov;16(11):867-72. Epub 2010 Aug 4.

Hassan A, Newman A, Ko DT, Rinfret S, Hirsch G, Ghali WA, Tu JV.; Department of Cardiac Surgery, New Brunswick Heart Center, Saint John, New Brunswick, Canada. Increasing rates of angioplasty versus bypass surgery in Canada, 1994-2005. Am Heart J. 2010 Nov;160(5):958-65.

James MT, Ghali WA, Tonelli M, Faris P, Knudtson ML, Pannu N, Klarenbach SW, Manns BJ, Hemmelgarn BR. Acute kidney injury following coronary angiography is associated with a long-term decline in kidney function. Kidney Int. 2010 Oct;78(8):803-9. Epub 2010 Aug 4.

Oreopoulos A, Padwal R, McAlister FA, Ezekowitz J, Sharma AM, Kalantar-Zadeh K, Fonarow GC, Norris CM. Association between obesity and health-related quality of life in patients with CAD. Int J Obes (Lond). 2010 Sep;34(9):1434-41. Epub 2010 Apr 13.

Johansen H, Brien S, Finès P, Bernier J, Humphries K, Stukel T, Ghali W; for the Canadian Cardiovascular Outcomes Research Team. Thirty-day in-hospital revascularization and mortality rates after acute myocardial infarction in seven Canadian provinces. Can J Cardiol. 2010 Aug/Sept;26(7):243-248.

Taylor CM, Humphries KH, Pu A, Ghali W, Gao M, Knudtson M, Hoffmann U, Carere RG. A proposed clinical model for efficient utilization of invasive coronary angiography. Am J Cardiol. 2010 Aug 15;106(4):457-62.

Norris CM, Murray JW, Tripplett LS, Hegadoren KM. Gender roles in persistent sex differences in health-related quality-of-life outcomes of patients with coronary artery disease. Gend Med. 2010 Aug; 7(4): 330-39.

Oreopoulos A, Ezekowitz JA, McAlister FA, Kalantar-Zadeh K, Fonarow GC, Norris CM, Johnson JA, Padwal RS. Association between direct measures of body composition and prognostic factors in chronic heart failure. Mayo Clin Proc. 2010 Jul;85(7):609-17.

Quan H, Khan N, Li B, Humphries K, Faris P, Galbraith P, Graham M, Knudtson M, Ghali W. Invasive cardiac procedure use and mortality among South Asian and Chinese Canadians with coronary artery disease. Can J Cardiol. 2010 Jul;26(7):236-42.

Cantor WJ, Strauss BH, Graham MM, Southern DA, Woo K, Tyrrell B, Knudtson M, Ghali WA. Time of day and outcomes of nonurgent percutaneous coronary intervention performed during working hours. Am Heart J. 2010 Jun;159(6):1133-8.

Deyell MW, Ghali WA, Ross DB, Zhang J, Hemmelgarn BR; Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) Investigators. Timing of nonemergent coronary artery bypass grafting and mortality after non-ST elevation acute coronary syndrome. Am Heart J. 2010 Mar;159(3):490-6.

Patel AB, Tu JV, Waters NM, Ko DT, Eisenberg MJ, Huynh T, Rinfret S, Knudtson ML, Ghali WA. Access to primary percutaneous coronary intervention for ST-segment elevation myocardial infarction in Canada: a geographic analysis. OpenMedicine. 2010;4(1).

Rabi DM, Edwards AL, Svenson LW, Graham MM, Knudtson ML, Ghali WA on behalf of the Alberta Provincial Project for Assessing Outcomes in Coronary Heart Disease Investigators. Association of Median Household Income With Burden of Coronary Artery Disease Among Individuals With Diabetes. Circ Cardiovasc Qual Outcomes Jan2010; 3(1):54-62.

McAlister FA, Fradette M, Majumdar SR, Williams R, Graham M, McMeekin J, Ghali WA, Tsuyuki RT, Knudtson ML, Grimshaw J. The Enhancing Secondary Prevention in Coronary Artery Disease trial. CMAJ. 2009 Dec 8;181(12):897-904. Epub 2009 Nov 23.

McFarlane A, Wielgosz A (Knudtson M); A Canadian Heart Health Strategy and Action Plan Theme Working Group 1. Cardiol 2009 Nov;25(11):631-4.

Oreopoulos A, McAlister FA, Kalantar-Zadeh K, Padwal R, Ezekowitz JA, Sharma AM, Kovesdy CP, Fonarow GC, Norris CM. The relationship between body mass index, treatment, and mortality in patients with established coronary artery disease: a report from APPROACH. Eur Heart J. 2009 Nov;30(21):2584-92. Epub 2009 Jul 16.

Shahid R, Bertazzon S, Knudtson ML, Ghali WA. Comparison of distance measures in spatial analytical modeling for health service planning. BMC Health Serv Res 2009 Nov 6;9(1):200.

Norris CM, Ljubsa A, Hegadoren KM. Gender as a determinant of responses to a self-screening questionnaire on anxiety and depression by patients with coronary artery disease. Gend Med. 2009 Sep;6(3):479-87.

King KM, Norris CM, Knudtson ML, Ghali WA for the APPROACH Investigators. Risk-taking attitudes and their association with process and outcomes of cardiac care: a cohort study. BMC Cardiovasc Disord. 2009 Aug 6;9:36.

Mancini GB, Bates ER, Maron DJ, Hartigan P, Dada M, Gosselin G, Kostuk W, Sedlis SP, Shaw LJ, Berman DS, Berger PB, Spertus J, Mavromatis K, Knudtson M, Chaitman BR, O'Rourke RA, Weintraub WS, Teo K, Boden WE; COURAGE Trial Investigators and Coordinators. Quantitative results of baseline angiography and percutaneous coronary intervention in the COURAGE trial. Circ Cardiovasc Qual Outcomes. 2009 Jul;2(4):320-7. Epub 2009 Jun 2.

Knudtson ML, Norris CM, Galbraith PD, Hubacek J, Ghali WA. Explicit Risk in Acute Coronary Syndrome Management. Can J Cardiol. 2009 Jun; 25 Suppl A:29A-36A. Review.

Norris CM, King K. A qualitative examination of the factors that influence women's quality of life as they live with coronary artery disease. West J Nurs Res. 2009 Jun;31(4):513-24. Epub 2009 Feb 10.

Austin D, Oldroyd KG, Holmes DR, Rihal CS, Galbraith PD, Ghali WA, Legrand V, Taeymans Y, McConnachie A, Pell JP, on behalf of the APPROACH Investigators, Belgian Working Group on Invasive Cardiology, Mayo Clinic PCI Registry, and Scottish Coronary Revascularisation Registry Glasgow, United Kingdom; Rochester, MN; Calgary, Canada; and Liege, and Gent, Belgium. Drug-eluting stents: A study of international practice. Am Heart J 2009;158:576-84.

Mohamed R, McAlister FA, Pretorius V, Kapoor AS, Majumdar SR, Ross DB, and Norris CM for the APPROACH Investigators. Preoperative statin use and infection after cardiac surgery: a cohort study. Clin Infect Dis. 2009 Apr 1;48(7):e66-72.

King KM, Southern DA, Cornuz J, Maitland A, Knudtson, ML, Ghali WA. Elevated Body Mass Index and Use of Coronary Revascularization after Cardiac Catheterization. Am J Med 2009 Mar;122(3):273-80.

Norris CM, Patterson L, Galbraith D, Hegadoren KM. All you have to do is call; a pilot study to improve the outcomes of patients with coronary artery disease. Appl Nurs Res 2009:22(2);133-137.

Philpott A, Southern DA, Clement FM, Galbraith PD, Traboulsi M, Knudtson ML, Ghali WA for the APPROACH Investigators. Long term outcomes of patients receiving drug eluting stents. CMAJ 2009 Jan:180(2);167-174.

Chow BJW, Abraham A, Wells GA, Chen L, Ruddy TD, Yam Y, Govas N, Galbraith PD, Dennie C, Beanlands RS. Diagnostic accuracy and impact of computed tomographic coronary angiography on utilization of invasive coronary angiography. CIRC Cardiovasc Imaging 2009: 2;16-23.

Woo KS, Ghali WA, Southern DA, Tu JV, Parsons G, Graham MM. Feasibility of determining myocardial infarction type from medical record view. Can J Cardiol. 2008 Feb;24(2):115-117.

Schmaltz HN, Southern DA, Maxwell CJ, Knudtson ML, Ghali WA; for the APPROACH Investigators. Patient Sex Does Not Modify Ejection Fraction as a Predictor of Death in Heart Failure: Insights from the APPROACH Cohort. J Gen Intern Med. 2008 Dec;23(12):1940-6.

Ko DT, Donovan LR, Huynh T, Rinfret S, So DY, Love MP, Galbraith D, Tu JV; Canadian Cardiovascular Outcomes Research Team (CCORT). A survey of primary percutaneous coronary intervention for patients with ST segment elevation myocardial infarction in Canadian hospitals. Can J Cardiol. 2008 Nov;24(11):839-43.

Gyenes GT, Ghali WA. Should all patients with asymptomatic but significant (>50%) left main coronary artery stenosis undergo surgical revascularization? Circulation. 2008 Jul 22;118(4):422-5. (Clinician update).

Oreopoulos A, Padwal R, Kalantar-Zadeh K, Fonarow GS, Norris CM, McAlister FA. Body mass index and mortality in heart failure: a meta-analysis. Am Heart J 2008;156(1):13-22.

Norris CM, Hegadoren K, Patterson L, Pilote L. Sex differences in prodromal symptoms of patients with acute coronary syndrome: a pilot study. Prog Cardiovasc Nurs 2008;28(1):27-31.

Oreopoulos A, Padwal R, Norris CM, Mullen JC, Pretorius V, Kalantar-Zadeh K. Effect of obesity on short- and long-term mortality post-coronary revascularization: a meta-analysis. Obesity 2008;16(2);442-450.

Hubacek J, Kalla S, Galbraith PD, Graham MM, Knudtson ML, Ghali WA, for the APPROACH Investigators. Outcomes of revascularization strategies for two vessel coronary artery disease involving the proximal left anterior descending artery in an era of improved pharmacotherapy and stenting. Can J Cardiol 2008: 24(2);121-126.

Southern DA, Norris CM, Quan H, Shrive FM, Galbraith PD, Humphries K, Gao M, Knudtson ML, Ghali WA. An administrative data merging solution for dealing with missing data in a clinical registry: adaptation from ICD-9 to ICD-10. BMC Med Res Methodol. 2008 Jan 23; 8( 1): 1.

Makowsky MJ, McAlister FA, Galbraith PD, Southern DA, Ghali WA, Knudtson ML, Tsuyuki, RT for the Alberta Provincial Program for Outcome Assessment in Coronary Heart Disease (APPROACH) Investigators. Lower extremity peripheral arterial disease in individuals with coronary artery disease: Prognostic importance, care gaps, and impact of therapy. Am Heart J 2008;155:348-55.

Goldberg A, Southern DA, Galbraith PD, Traboulsi M, Knudtson ML, Ghali WA for the APPROACH Investigators. Coronary dominance and prognosis of patients with acute coronary syndrome. Am Heart J 2007 Dec;154:1116-22.

Patel AB, Waters NM, Ghali WA. Determining geographic areas and populations with timely access to cardiac catheterization facilities for acute myocardial infarction care in Alberta, Canada. Intl J Health Geog 2007 Oct 16; 6:47.

Bainey KR, Norris CM, Graham MM, Ghali WA, Knudtson ML, Welsh RC for the APPROACH Investigators. Clinical in-stent restenosis with bare metal stents: Is it truly a benign phenomenon? Intl Journal of Cardiology, 2008 Aug 29;128(3):378-82. online publication Aug 2007.

Worthley MI, Shrive FM, Anderson TJ, Traboulsi M. Prognostic Implication of Hyperglycemia in Myocardial Infarction and Primary Angioplasty. Am J Med, 2007 Jul, Vol 120, Issue 7: 643.e1-643.e7.

Quan H, Galbraith PD, Norris CM, Southern DA, King K, Verhoef MJ, Knudtson ML, Ghali WA. Opinions on chelation therapy in patients undergoing coronary angiography: cross-sectional survey. Can J Cardiol. 2007 Jun;23(8):635-40.

McAlister FA, Oreopoulos A, Norris CM, Graham MM, Tsuyuki RT, Knudtson M, Ghali WA. Exploring the Treatment-Risk Paradox in Coronary Disease. Arch Intern Med. 2007 May 28;167(10):1019-1025.

Schmaltz HN, Southern D, Ghali WA, Jelinski SE, Parsons GA, King KM, Maxwell CJ. Living alone, patient sex and mortality after acute myocardial infarction. J Gen Intern Med. 2007 May;22(5):572-8.

Shrive FM, Tsuyuki RT. Bias in revascularization study. CMAJ. 2007 Apr 10;176(8):1125. Response to letter. https://dx.doi.org/10.1503%2Fcmaj.1060238

Ray JG, Norris CM, Udell JA, Tsuyuki RT, McAlister FA, Knudtson ML, Ghali WA. Lipid-lowering therapy and outcomes in heart failure. J Cardiovasc Pharmacol Ther. 2007 Mar;12(1):27-35.

Shrive FM, Ghali WA, Johnson JA, Donaldson C, Manns BJ. Use of the U.S. and U.K. scoring algorithm for the EuroQol-5D in an economic evaluation of cardiac care. Med Care. 2007 Mar;45(3):269-73.

Knudtson ML. Drug-eluting coronary stents: faith and hope, but no charity. CMAJ. 2007 Jan 16;176(2):195

ML Ackman, Graham MM, Hui C, Ross TT. Effect of a prior authorization process on antiplatelet therapy and outcomes in patients prescribed clopidogrel following coronary stenting. Can J Cardiol. 2006 Dec;22(14):1205-1208.

Shrive FM, Stuart H, Quan H, Ghali WA. Dealing with missing data in a multi-question depression scale: a comparison of imputation methods. BMC Med Res Methodol. 2006 Dec 13;6:57.

Bagshaw SM, Galbraith PD, Mitchell LB, Sauve R, Exner DV, Ghali WA. Prophylactic amiodarone for prevention of atrial fibrillation after cardiac surgery: a meta-analysis. Ann Thorac Surg. 2006 Nov;82(5):1927-37.

Southern DA, Faris PD, Brant R, Galbraith PD, Norris CM, Knudtson ML, Ghali WA, for the APPROACH Investigators. Kaplan - Meier methods yielded misleading results in competing risk scenarios. J Clin Epidemiol 2006 Oct; 59(10):1110-4.

Tsuyuki RT, Shrive FM, Galbraith PD, Knudtson ML, Graham MM, for the APPROACH Investigators. Revascularization in Patients with Heart Failure. CMAJ 2006 Aug. 15; 175(4):361-5.

Knudtson, ML, Beanlands R, Brophy JM, Higginson L, Munt B, Rottger J on behalf of the Canadian Cardiovascular Society Access to Care Working Group. Treating the right patient at the right time: Access to specialist consultation and noninvasive testing. Can J Cardiol 2006 Aug;22(10):819-824.

Ross H, Howlett J, Arnold JM, Liu P, O'Neill BJ, Brophy JM, Simpson CS, Sholdice MM, Knudtson M, Ross DB, Rottger J, Glasgow K; Canadian Cardiovascular Society Access to Care Working Group. Treating the right patient at the right time: access to heart failure care. Can J Cardiol. 2006 Jul;22(9):749-54.

Graham MM, Knudtson ML, O'Neill BJ, Ross DB for the Canadian Cardiovascular Society Access to Care Working Group. Treating the right patient at the right time: Access to cardiac catheterization, percutaneous coronary intervention and cardiac surgery. Can J Cardiol 2006 July; 22(8): 679-683.

Graham MM, Norris CM, Galbraith PD, Knudtson ML, Ghali WA. Quality of life after coronary revascularization in the elderly. Eur Heart J 2006 July; 27(14):1690-8.

Gyenes G, Shrive FM, Graham MM, Ghali WA, Knudtson ML for the APPROACH Investigators. The Prognostic Importance of Nonsignificant Left Main Coronary Artery Disease in Patients Undergoing Percutaneous Coronary Intervention. J Am Coll Cardiol. 2006 Jul 18;48(2):276-80.

McAlister FA, Ghali WA, Gong Y, Fang J, Armstrong PW, Tu JV. Aspirin use and outcomes in a community-based cohort of 7352 patients discharged after first hospitalization for heart failure. Circulation. 2006 Jun 6;113(22):2572-8.

Hemmelgarn BR, Southern DA, Humphries KH, Culleton BF, Knudtson ML, Ghali WA for the APPROACH Investigators. Refined characterization of the association between kidney function and mortality in patients undergoing cardiac catheterization. Eur Heart J 2006 May;27(10):1191-7.

Norris CM, Ghali WA, Saunders LD, Brant R, Galbraith D, Faris P, Knudtson ML, for the APPROACH Investigators. Ordinal regression model and the linear regression model were superior to the logistic regression models. J Clin Epidemiol 2006 May; 59(5):448-56.

Ghali WA, Noseworthy TW . In search of 'truth' and standards for reporting cardiac procedure waiting times. Can J Cardiol. 2006 May 1;22(6):503-4. No abstract available.

Quan H, Wang F, Schopflocher D, Norris C, Galbraith PD, Faris P, Graham MM, Knudtson ML, and Ghali WA. Development and Validation of a Surname List to Define Chinese Ethnicity. Med Care. 2006 Apr;44(4):328-33.

Southern DA, Faris PD, Knudtson ML, Ghali, WA, for the APPROACH Investigators. Prognostic relevance of census-derived individual respondent incomes versus household incomes. Can J Public Health 2006 Mar-Apr; 97(2):114-7.

Hubacek J, Galbraith PD, Gao M, Humphries K, Graham MM, Knudtson ML, Ghali WA for the APPROACH Investigators. External validation of a percutaneous coronary intervention mortality prediction model in patients with acute coronary syndromes. Am Heart J 2006 Feb;151:308-15.

Southern DA, Knudtson ML, Ghali, WA, for the APPROACH Investigators. Myocardial infarction on snow days: incidence, procedure use and outcomes. Cardiol 2006 Jan; 22(1):59-61.

Southern DA, McLaren L, Hawe P, Knudtson ML, Ghali WA, for the APPROACH Investigators. Individual-Level and Neighborhood-Level Income Measures: Agreement and Association With Outcomes in a Cardiac Disease Cohort. Med Care 2005 Nov; 43:1116–1122.

McLellan CS, Ghali WA, Labinaz M, Davis R, Galbraith D, Southern D, Shrive F, Knudtson ML, for the APPROACH Investigators. Association between completeness of percutaneous coronary revascularization and post-procedure outcomes. Am Heart J 2005 Oct; 150(4):800-806.

Alagiakrishnan K, Beitel JD, Graham MM, Southern DA, Knudtson ML, Ghali WA, Tsuyuki RT for the APPROACH Investigators. Relation of T-Axis Abnormalities to Coronary Artery Disease and Survival after Cardiac Catheterization. Am J Cardiol 2005 Sep 1; 96:639-642.

Shrive FM, Ghali WA, Lewis S, Donaldson C, Knudtson ML, Manns BJ. Moving beyond the cost per quality-adjusted life year: Modelling the budgetary impact and clinical outcomes associated with the use of sirolimus-eluting stents. Can J Cardiol 2005 Jul 9; 21(9): 783-787.

Graham MM, Ghali WA, Faris PD, Galbraith PD, Tu JV, Norris CM, Zentner A, Knudtson ML. Population rates of cardiac catheterization and yield of high-risk coronary artery disease. CMAJ 2005 Jul 5; 173 (1):35-39.

Humphries KH, Carere RG, Izadnegahdar M, Galbraith PD, Knudtson ML, Ghali WA. Cross-provincial use of cardiac services: The importance of data-sharing for clinical registries and outcomes research. Can J Cardiol 2005 Mar 1;21(3):267-272.

Shrive, FM, Manns BJ, Galbraith PD, Knudtson ML, Ghali WA; Economic evaluation of sirolimus-eluting stents. CMAJ 2005 Feb 1; 172 (3): 345-351.

Cornuz, J, Faris P, Galbraith PD; Knudtson ML, Ghali WA; Absence of bias against smokers in access to coronary revascularization after cardiac catheterization. Int J Qual Health Care 2005 Feb;17(1)37-42.

Larsen AI, Galbraith PD, Ghali WA, Norris CM, Graham MM, Knudtson ML. Characteristics and outcomes of patients with acute myocardial infarction and angiographically normal coronary arteries. Am J Cardiol 2005 Jan15; 95:261-263.

Thompson CR, Humphries KH, Gao M, Galbraith PD, Norris C, Carere RG, Knudtson ML, Ghali WA (Canadian Cardiovascular Outcomes Research Team); Revascularization use and survival outcomes after cardiac catheterization in British Columbia and Alberta. Can J Cardiol. 2004 Dec14;20(14):1417-23.

Norris CM, Jensen LA, Galbraith PD, Graham MM, Daub WD, Knudtson ML, Ghali WA. Referral Rate and Outcomes of Cardiac Rehabilitation After Cardiac Catheterization in a Large Canadian City. Journal of Cardiopulmonary Rehabilitation 2004 Nov/Dec;24:392-400.

Ezekowitz J, McAlister FA, Humphries KH, Norris CM, Tonelli M, Ghali WA, Knudtson ML, for the APPROACH Investigators. The association between renal insufficiency, pharmacotherapy, and outcomes in 6,437 patients with heart failure and coronary artery disease. Journal of the American College of Cardiology. 2004 Oct19;44:1587-92.

Norris CM, Saunders LD, Ghali WA, Brant R, Galbraith PD, Graham M, Faris P, Dzavik V, Knudtson ML; Health-related quality of life outcomes of patients with coronary artery disease treated with cardiac surgery, percutaneous coronary intervention or medical management. Can J Cardiol. 2004 Oct 12;20(12):1259-66.

Hemmelgarn BR, Southern D, Culleton BF, Mitchell LB, Knudtson ML, Ghali WA for the APPROACH Investigators. Survival after coronary revascularization among patients with kidney disease. Circulation. 2004 Oct5;110:1890-95.

Appoo J, Norris C, Merali S, Graham MM, Koshal A, Knudtson ML, Ghali WA. Long-term outcome of isolated coronary artery bypass surgery in patients with severe left ventricular dysfunction. Circulation. 2004 Sept14;100(11 Suppl 1):II13-7.

Quan H, Ghali WA, Dean S, Norris CM, Galbraith PD, Faris PD, Graham MM, Knudtson ML. Validity of using surname to define Chinese ethnicity. Canadian Journal of Public Health 2004 Jul/Aug;95(4):314.

Norris CM, Ghali WA, Galbraith PD, Graham MM, Jensen LA, Knudtson ML, for the APPROACH Investigators. Women with coronary artery disease report worse health-related quality of life outcomes compared to men. Health Qual Life Outcomes. 2004 May5;2(1):21.

Seidel JE, Ghali WA, Faris PD, Bow CJD, Waters NM, Graham MM, Galbraith PD, Mitchell LB, Knudtson ML for the APPROACH Investigators. Geographical location of residence and access to cardiac revascularization services. Can J Cardiol 2004 Apr 5; 20(5) :517-523.

Bow CJ, Waters NM, Faris PD, Seidel JD, Galbraith PD, Knudtson ML, Ghali WA for the APPROACH Investigators. Accuracy of city postal code coordinates as a proxy for location of residence. Int J Health Geogr 2004 Mar18; 3(1):5.

Faris PD, Grant FC, Galbraith PD, Gong Y, Ghali WA. Diagnostic cardiac catheterization and revascularization rates for coronary heart disease. Can J Cardiol. 2004 Mar 15;30(4):391-7.

Westerhout CM, Saunders LD, Kaul P, Armstrong PA, Knudtson ML, Ghali WA on behalf of the APPROACH Investigators. Interinstitutional variation in the use of abciximab for percutaneous coronary intervention. Can J Cardiol 2004 Mar 15;20(4):405-410.

King KM, Ghali WA, Faris PD, Curtis MJ, Galbraith PD, Graham MM, Knudtson ML. Sex differences in outcomes after cardiac catheterization: effect modification by treatment strategy and time. JAMA. 2004 Mar 10;291(10):1220-5.

Norris CM, Ghali WA, Saunders LD, Brant R, Galbraith PD. Systematic review of statistical methods used to analyze Seattle Angina Questionnaire scores. Cardiol 2004 Feb2; 20(2):187-193.

Graham MM, Ghali WA, Faris PD, Galbraith PD, Norris CM, Knudtson ML for the APPROACH Investigators. Sex differences in the prognostic importance of diabetes in patients with ischemic heart disease undergoing coronary angiography. Diabetes Care. 2003 Nov;26(11):3142-7.

Ghali WA, Donaldson CR, Knudtson ML, Lewis SJ, Maxwell CJ, Tu JV. Rising to the challenge: transforming care for ST-elevation myocardial infarction. CMAJ. 2003 Jul8;169:35-7.

Faris PD, Ghali WA, Brant R. Bias in estimates of confidence intervals for health outcome report cards. Journal of Clinical Epidemiology 2003 Jun;56:553-8.

The SOS Investigators. Coronary artery bypass surgery versus percutaneous coronary intervention with stent implantation in patients with multivessel coronary artery disease (the Stent or Surgery trial): a randomized controlled trial. Lancet. 2002; 360:965-970.

Southern DA, Ghali WA, Faris PD, Norris CM, Galbraith PD, Graham MM, Knudtson ML for the APPROACH Investigators. Misclassification of income quintiles derived from area-based measures: a comparison of enumeration area and forward sortation area. Can J Public Health 2002 Nov/Dec; 93(6):465-469.

Graham MM, Ghali WA, Faris PD, Galbraith PD, Norris CM and Merril Knudtson for the APPROACH Investigators. Survival after coronary revascularization in the elderly. Circulation 2002 May21;105(20):2378-84.

Ghali WA, Faris PD, Galbraith PD, Norris CM, Curtis MJ, Saunders LD, Dzavik V, Mitchell LB, Knudtson ML. Sex differences in access to coronary revascularization after cardiac catheterization: importance of detailed clinical data. Ann Intern Med 2002 May21;136(10):723-32.

Faris PD, Ghali WA, Brant R, Norris CM, Galbraith PD, Knudtson ML for the APPROACH Investigators. Multiple imputation versus data enhancement for dealing with missing data in observational health care outcome analyses. J Clin Epidem 2002 Feb;55(2):184-191.

Quan H, Ghali WA, Verhoef MJ, Norris CM, Galbraith PD, and Knudtson ML. Use of chelation therapy after coronary angiography. Am J Med 2001 Dec15;111(9):686-691.

Ghali WA, Graham MM. Evidence or faith? Coronary artery bypass surgery in the elderly. CMAJ 2001 Sep18;165:783-5. (Commentary) https://www.ncbi.nlm.nih.gov/pubmed/11584565

Ghali WA, Quan H, Brant R, van Melle G, Norris CM, Faris PD and Knudtson ML for the APPROACH Investigators. A comparison of two methods for calculating adjusted survival curves from proportional hazards models. JAMA 2001 Sept26;286(12):1494-97.

Graham MM, Faris PD, Ghali WA, Galbraith PD, Norris CM, Badry JT, Mitchell LB, Curtis MJ and Knudtson ML for the APPROACH Investigators. Validation of three myocardial jeopardy scores in a population-based cardiac catheterization cohort. Am Heart J 2001 Aug; 142(2):254-61.

Dzavik V, Ghali WA, Norris CM, Mitchell B, Koshal A, Saunders DL, Galbraith PD, Hui W, Faris PD, Knudtson ML for the APPROACH Investigators. Long-term survival in 11,661 patients with multivessel disease coronary artery disease in an era of stenting: A report from APPROACH. Am Heart J 2001 Jul; 142(1):119-26.

Hemmelgarn BR, Ghali WA, Quan H, Brant R, Norris CM, Taub KJ, Knudtson ML. Poor long term survival after coronary angiography in patients with renal insufficiency. Am J Kidney Dis 2001 Jan;37(1):64-72.

Ghali WA, Quan H, Norris CM, Dzavik V, Naylor CD, Mitchel LB, Brant R, Knudtson ML. Prognostic significance of diabetes as a predictor of survival after cardiac catheterization. Am J Med 2000 Nov;109(7):543-8.

Ghali WA, Knudtson ML for the APPROACH Investigators. Overview of 'APPROACH' the Alberta provincial project for outcome assessment in coronary heart disease. Can J Cardiol 2000 Oct10; 16(10):1225-1230.

Norris CM, Ghali WA, Knudtson ML, Saunders LD, Naylor CD. Dealing with missing data in observational health care outcome analysis. J Clin Epidemiol. 2000 Apr;53:377-383. Am J Med 2000 Nov;109(7):543-8.